Product Name: Pregnenolone
Chemical Formula: C21H32O2
Other Names: 3β-Hydroxypregn-5-en-20-one
CAS Number: 145-13-1
Recommended Uses: Lab research, diagnostic reagent, research chemical
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Physical Hazards: Not flammable under normal conditions
Health Hazards: May cause irritation to the skin, eyes, and respiratory tract; may affect endocrine function after prolonged exposure; avoid direct contact
Environmental Hazards: Minimal risk to aquatic life in small quantities; avoid release to environment
Classification: Not classified as a hazardous substance or mixture according to OSHA Hazard Communication Standard
Label Elements: None required, still recommend good handling practices
Chemical Name: Pregnenolone
Purity: ≥ 98%
Mixture Components: No significant impurities or stabilizing additives
Inhalation: Move affected person into fresh air, keep comfortable for breathing, seek medical attention if symptoms occur
Skin Contact: Wash exposed area thoroughly with soap and water, remove any contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy, continue rinsing, get medical advice if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, seek medical advice immediately
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: Avoid high pressure water streams
Hazardous Combustion Products: Carbon oxides, smoke, toxic vapors
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Take care to avoid exposure to fumes, cool containers exposed to fire with water mist
Personal Precautions: Wear gloves, lab coat, safety glasses, avoid direct contact with substance
Environmental Precautions: Prevent further leakage or spillage if safe, don’t let product reach drains, water sources
Cleanup Methods: Pick up with inert absorbent, place in labeled container, ventilate area, wash spill site after material pickup is complete
Safe Handling: Wear protective equipment, avoid breathing dust or vapor, work in a well-ventilated area, avoid eating or drinking in work areas
Storage Conditions: Store tightly sealed in original container, place in cool, dry, well-ventilated space
Incompatibilities: Strong oxidizers, acids, bases—keep away from sources of heat or ignition
Specific Storage Requirements: Refrigerated recommended for long-term storage
Engineering Controls: Work in fume hood, use local exhaust ventilation for powder handling
Eye Protection: Safety goggles
Hand Protection: Disposable nitrile or latex gloves
Body Protection: Lab coat, suitable chemical resistant clothing
Respiratory Protection: Dust mask or respirator recommended if dust is generated
Hygiene Measures: Wash hands thoroughly after handling, do not eat or drink near the substance
Appearance: White to off-white crystalline powder
Odor: Odorless
Molecular Weight: 316.48
Solubility: Insoluble in water, soluble in ethanol, chloroform, DMSO
Melting Point: 181 - 184°C
Boiling Point: Not applicable (decomposes before boiling)
Vapor Pressure: Low
Density: 1.1 g/cm³ (approximate)
Reactivity: Stable under recommended storage and handling conditions
Chemical Stability: Not sensitive to normal temperature, decomposes on extreme heat
Possible Hazardous Reactions: Reacts with strong oxidants, acids, bases
Conditions to Avoid: High heat, flames, sources of ignition
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, toxic fumes
Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Effects: Irritation of respiratory tract, skin, and eyes
Chronic Effects: Not well-studied, may disrupt hormone levels with sustained exposure
LD50/LC50: No official data for humans; not acutely toxic in research animals at moderate exposure
Carcinogenicity: Not listed by IARC, OSHA, or NTP
Mutagenicity/Reproductive Toxicity: Data limited; avoid unnecessary exposure
Ecotoxicity: No specific data available, not expected to be acutely toxic to aquatic organisms in low concentrations
Persistence/Degradability: Not readily biodegradable
Bioaccumulation: No evidence for significant accumulation in organisms
Water Hazard Rating: Low, yet minimize exposure from release
Soil Mobility: Low mobility in soil
Waste Treatment Methods: Collect in safe, labeled container, arrange chemical disposal through licensed contractor
Disposal of Packaging: Triple rinse containers, dispose as controlled waste
Special Instructions: Do not discharge to sewers or environment, consult local and federal regulations
Disposal Code: Check with appropriate jurisdiction
UN Number: Not regulated for transport
Proper Shipping Name: Pregnenolone
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not assigned
Marine Pollutant: No
Precautions: Prevent package damage, avoid extreme temperatures
US Regulations: Not a controlled substance under DEA, not listed on TSCA, status may vary by state
EU Regulations: Not classified as hazardous under EU regulations, not subject to REACH restrictions
International Inventories: Verification needed for specific markets
Label Requirements: Standard research chemical labeling, institutional requirements may apply
Workplace Restrictions: Refer to local occupational safety and health guidelines for permissible amounts and practices
