Product Name: 5A-Pregnan-3B-Ol-20-One
Synonyms: Allopregnanolone, 3α-Hydroxy-5α-pregnan-20-one
Chemical Formula: C21H34O2
Molecular Weight: 318.5 g/mol
CAS Number: 516-54-1
Recommended Use: Laboratory research or chemical synthesis; not for human or veterinary drug use
Manufacturer: Use company or supplier contact from product packaging
Emergency Contact: Refer to local poison control or supplier contact listed on package
GHS Classification: Not classified as hazardous according to current Globally Harmonized System standards
Signal Word: Not applicable
Hazard Statements: Not considered a hazardous substance under typical handling, though dust inhalation or skin contact could irritate sensitive individuals
Precautionary Statements: Avoid breathing dust; wash hands thoroughly after handling
Potential Health Effects: Inhalation, skin, or eye contact could cause minor irritation
Environmental Hazards: Avoid release into environment; long-term effects unknown
Chemical Name: 5A-Pregnan-3B-Ol-20-One
Synonyms: Allopregnanolone
PURITY: >98% (based on supplier analysis)
Impurities: Trace byproducts from synthesis, none classified as hazardous
Stabilizers: None indicated
Inhalation: Move person into fresh air; monitor for discomfort; call doctor if symptoms persist
Skin Contact: Wash with plenty of soap and water; immediate rinsing; remove contaminated clothing
Eye Contact: Rinse under running water for at least 15 minutes; seek medical advice if irritation occurs
Ingestion: Rinse mouth with water; never give anything by mouth to an unconscious person; seek medical attention
Notes to Physician: No specific antidote; treat symptomatically
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Specific Hazards: Combustion releases carbon oxides (CO/CO2), minor organic fragments
Protective Equipment: Firefighters should use self-contained breathing apparatus and protective clothing
Fire-Fighting Instructions: Keep unnecessary people away from area, cool containers with water if exposed to flames
Personal Precautions: Wear dust mask, gloves, eye protection
Spill Response: Sweep or scoop up with minimal dust; avoid dry sweeping; place in suitable closed container for disposal
Cleanup Methods: Wash area with water after removal; prevent runoff into drains or water systems
Environmental Precautions: Do not release large quantities into soil or waterways
Safe Handling: Use in a well-ventilated area; avoid creating dust; wear appropriate safety gear
Storage Conditions: Store at room temperature in a tightly closed container; keep away from direct sunlight, heat, and moisture
Incompatibilities: Strong oxidizers, acids
Hygiene Measures: Wash hands after use; avoid eating, drinking, or smoking during handling
Engineering Controls: Use local exhaust ventilation or work in fume hood
Personal Protective Equipment (PPE): Laboratory gloves (nitrile recommended), safety goggles, lab coat
Respiratory Protection: NIOSH-approved dust respirator if ventilation inadequate
Exposure Limits: No occupational exposure limits established for this compound
Environmental Controls: Prevent dust accumulation; avoid release into drains
Appearance: White to off-white crystalline powder
Odor: Odorless or faint organic scent
Melting Point: About 162 - 165°C
Boiling Point: Not determined, decomposes
Flash Point: Not established, likely high due to low volatility
Solubility: Practically insoluble in water; soluble in ethanol, chloroform, and other organic solvents
Vapor Pressure: Negligible at room temperature
pH: Not applicable (solid)
Partition Coefficient (log Kow): Estimated above 3 (lipophilic)
Density: Approx. 1.08 g/cm3
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Non-reactive under normal laboratory conditions; avoid exposure to oxidizers
Conditions to Avoid: High temperatures, direct flaming, strong acids or oxidizers
Decomposition Products: Carbon oxides, possible low molecular weight organic fragments if burned
Polymerization: Does not occur
Acute Toxicity: Data not established in humans; considered low based on chemical structure and animal studies
Skin/Eye Irritation: May cause mild, transient irritation
Respiratory Sensitization: Not reported
Carcinogenicity: No evidence from available data
Reproductive Effects: Not well studied, consult a toxicologist
Target Organ Effects: No chronic effects reported in standard assays
Ecotoxicity: No specific data; do not allow into waterways due to possible persistence and bioaccumulation
Persistence/Degradability: Likely stable in the environment; slow degradation
Bioaccumulation: Potential due to fat-soluble nature
Mobility in Soil: Low, binds to organic matter
Other Adverse Effects: Unlikely to cause acute aquatic toxicity, precaution suggested
Waste Handling: Collect and place in sealed, labeled container
Disposal Methods: Dispose of according to local, regional, and national regulations for chemical waste
Contaminated Packaging: Dispose of empty containers as hazardous waste after triple-rinse
Special Precautions: Do not flush to sewer or allow material to reach public water systems
UN Number: Not assigned
UN Proper Shipping Name: Not regulated for transport
Transport Hazard Class: Not regulated
Packing Group: Not classified
Special Precautions: Keep containers tightly sealed, protect from physical damage during transport
DOT/IATA/IMDG/ADR/RID: No special provisions or restrictions listed
OSHA Status: Not listed as hazardous according to OSHA
TSCA: Listed for research and development use
DSL/NDSL: Not listed in Canadian inventory
SARA Title III: Not subject to SARA Title III reporting
California Proposition 65: Not listed
Other Regulations: Users should verify local and state requirements for chemical safety and reporting
Workplace Labeling: Ensure secondary containers are labeled in compliance with standard laboratory practice
