Product Name: 5-Pregnen-3B-Ol-20-One Synonyms: Pregnenolone, 3β-Hydroxy-5-pregnen-20-one CAS Number: 145-13-1 Molecular Formula: C21H32O2 Recommended Use: Laboratory chemical, chemical synthesis intermediate Supplier Details: Name, address, and phone number of the manufacturer or supplier; emergency contact Emergency Number: 24-hour health and safety assistance line
Classification: Not classified as a hazardous material under GHS guidelines, but dust generation can irritate respiratory system Signal Word: None required Hazard Statements: Potential skin and eye irritant; inhalation may cause temporary respiratory discomfort Pictograms: No GHS pictogram required Precautionary Statements: Avoid breathing dust, wash hands after handling, use protective eyewear Other Hazards: Long-term environmental impacts not well-studied
Chemical Name: 5-Pregnen-3B-Ol-20-One Concentration: Greater than 98% Impurities: Less than 2%, typical byproducts from synthesis Chemical Family: Steroid EC Number: 205-624-3 Ingredient Notes: No hazardous additives present
Inhalation: Move person to fresh air, keep comfortable, seek medical advice if symptoms persist Skin Contact: Remove contaminated clothing, wash exposed area with soap and water Eye Contact: Rinse carefully with water for a few minutes, remove contact lenses if easy, continue rinsing Ingestion: Rinse mouth with water, do not induce vomiting, seek medical attention if large quantity swallowed Most Important Symptoms: May cause temporary irritation to skin, eyes, respiratory tract Notes to Physician: Symptomatic treatment only
Suitable Extinguishing Media: Water spray, dry chemical powder, foam, carbon dioxide Special Protective Equipment: Wear full protective gear and self-contained breathing apparatus Specific Hazards: Combustion may release irritating or toxic fumes, carbon oxides possible Firefighting Instructions: Keep containers cool with spray, avoid inhaling smoke or vapors Explosion Risk: No special risk of explosion in usual conditions
Personal Precautions: Use gloves, goggles, dust mask; ventilate area well Spill Cleanup: Sweep up material, avoid raising airborne dust; place into suitable container for disposal Environmental Precautions: Prevent entry into drains, sewers, or watercourses Decontamination: Wash spill area with water and mild soap after removal Disposal: Dispose of sweepings and residue in accordance with local regulations
Safe Handling Advice: Use only in well-ventilated areas, avoid generation of dust, avoid contact with skin and eyes Storage Conditions: Store in tightly closed container, keep in a cool, dry, well-ventilated place, protect from light Incompatible Materials: Strong oxidizing agents Hygiene Practices: Wash hands thoroughly after handling; do not eat, drink, or smoke during use
Engineering Controls: Local exhaust ventilation, fume hood for large-scale handling Personal Protective Equipment: Safety goggles, chemical-resistant gloves, lab coat Respiratory Protection: Dust mask or respirator if dust level exceeds exposure limit Exposure Guidelines: No occupational exposure limits established for this material Other Controls: Emergency eyewash station and safety shower in work area
Appearance: White to off-white crystalline powder Odor: Odorless Melting Point: 186–192°C Boiling Point: Decomposes before boiling Solubility: Poorly soluble in water, soluble in ethanol, chloroform, DMSO Vapor Pressure: Negligible at ambient temperature Flash Point: Not applicable due to solid form Density: Approximately 1.1 g/cm³ Stability in Air: Stable under recommended handling conditions pH: Not applicable
Chemical Stability: Stable at room temperature; keep away from strong heat and light Reactive Materials: Avoid strong oxidizers Decomposition Products: On combustion, may yield carbon oxides and traces of other organic compounds Polymerization: Will not polymerize under normal use Special Conditions: Excessive heat may lead to decomposition
Acute Toxicity: Data limited; no signs of acute toxicity in typical use levels Skin Corrosion/Irritation: May cause mild irritation in sensitive individuals Eye Damage/Irritation: Possible irritation on direct contact Respiratory Effects: Dust can temporarily irritate airways Long-Term Effects: No established evidence for chronic toxicity Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA Other Data: Endocrine-modulating properties noted in animal models, not fully established in human exposure
Aquatic Toxicity: Data lacking, precaution advised to limit environmental discharge Persistence: Chemical structure suggests slow biodegradation Bioaccumulation Potential: Lipophilic nature hints at possible accumulation in aquatic species Mobility: Expected low in soil due to low solubility in water Other Concerns: Components may pose risk to aquatic ecosystems if released in quantity
Waste Disposal Methods: Collect and place into tightly-sealed containers; deliver to approved chemical disposal site Container Handling: Triple-rinse empty containers, follow regulations for hazardous chemical residues Contaminated Packaging: Treat packaging as chemical waste; recycle or dispose through licensed service Regulatory Disposal: Comply with local, state, national rules for disposal Do Not: Release to sewers or surface waters
UN Number: Not regulated for transport Transport Hazard Class: Not classified as hazardous Packing Group: None assigned Label Required: No special label required Transport Precautions: Protect containers from crushing; use secondary containment during bulk transport
TSCA Inventory: Listed REACH Registration: Exempt or registered as required SARA Title III: Not listed as a hazardous or extremely hazardous substance California Prop 65: Not identified as a carcinogen or reproductive toxin Other Local/State Regulation: Varies by jurisdiction; lab chemicals typically require storage logs and handling records Workplace Management: Track usage, report accidental releases, and use PPE as outlined
